PUBLICATIONS
Citations: 1,553 ; H-Index: 18
(https://scholar.google.com/citations?hl=pt-PT&user=LkVk8wEAAAAJ&view_op=list_works&sortby=pubdate)
Top 5 [first-author and last (PI)] papers (in the last 5 years]:
1. SILVA, MONYQUE; NICOLETI, VITORIA; RODRIGUES, BARBARA; ARAUJO, ADEMIR; ELLWANGER, JOEL; ALMEIDA, JAMES; LEMOS, LEANDRO NASCIMENTO. Exploring deep learning in phage discovery and characterization. VIROLOGY, 609. (Impact Factor: 2.4). This work was developed and coordinated by me at Ilum/ CNPEM, in collaboration with a student from the same institution, as part of our ongoing efforts to innovate in computational virology. This review explores the recent revolution in bacteriophage research, focusing on the integration of deep learning algorithms with metagenomic data analysis. We examine how neural networks and pre-trained language models have been applied to uncover novel bacteriophages and elucidate their biological characteristics. The article highlights key aspects of phage biology through the lens of artificial intelligence, emphasizing both the advances and current limitations of deep-learning-based approaches. Finally, we present perspectives for the future development of metagenomic tools powered by AI and provide recommendations to guide upcoming research efforts.
2. LEMOS, LEANDRO NASCIMENTO et al. Large Scale Genome-Centric Metagenomic Data from the Gut Microbiome of Food-Producing Animals and Humans. SCIENTIFIC DATA, 9:366. (Impact Factor: 6.9). This study generated one of the largest genome-centric metagenomic datasets from animal and human gut microbiomes, promoting open data sharing and reproducibility. It supports cross-species One Health investigations and enables comparative microbiome studies. The data contributes directly to ongoing efforts to map microbial functions across hosts.
3. LEMOS, LEANDRO NASCIMENTO; MENDES, LUCAS WILLIAM ; BALDRIAN, P. ; Pylro, V. . Genome-Resolved Metagenomics Is Essential for Unlocking the Microbial Black Box of the Soil. TRENDS IN MICROBIOLOGY, v. 29, p. 279-282, 2021. (Impact Factor: 14.9). This perspective article highlights the critical role of genome-resolved metagenomics in advancing soil microbiome research. It influenced methodological choices in my projects and emphasized the need for high-resolution approaches in understanding ecosystem functions. Its broad citation potential reflects its theoretical and technological relevance.
4. LEMOS, LEANDRO NASCIMENTO; PEDRINHO, ALEXANDRE ; VASCONCELOS, ANA TEREZA RIBEIRO DE ; TSAI, SIU MUI ; MENDES, LUCAS WILLIAM. Amazon deforestation enriches antibiotic resistance genes. SOIL BIOLOGY & BIOCHEMISTRY, v. 153, p. 108110, 2021. (Impact Factor: 10.3). This work revealed how anthropogenic disturbance affects resistome, with serious implications for public health and conservation. It integrates ecological and molecular perspectives, informing environmental policies and microbial risk assessment. It directly supports my research on the impacts of land use on microbial communities.
5. LEMOS, LEANDRO NASCIMENTO; MEDEIROS, JULLIANE D. ; DINI'ANDREOTE, FRANCISCO ; FERNANDES, GABRIEL R. ; VARANI, ALESSANDRO M. ; OLIVEIRA, GUILHERME ; PYLRO, VICTOR S. Genomic signatures and co-occurrence patterns of the ultra-small Saccharimonadia ( CPR /Patescibacteria phylum) suggest a symbiotic lifestyle. MOLECULAR ECOLOGY, v. 28, p. 4259-4271, 2019. (Impact Factor: 3.9). This paper sheds light on the poorly understood CPR lineages, indicating their symbiotic lifestyle through genomic and ecological evidence. It is a significant contribution to microbial ecology, having opened new research avenues into uncultivated microbial groups, which aligns with my current projects on microbial interactions and hidden diversity.